International Journal of Advanced Multidisciplinary Research and Studies
Volume 2, Issue 6, 2022
Study of Uric acid and Serum Creatinine in Diabetic and Non-Diabetic patients in a tertiary hospital, Dhaka
Author(s): Md. Ashiqur Rahman, Sadia Islam, Marzan Islam Lubaba, Arifa Akram
Introduction: Diabetes mellitus (DM) type 2 is one of the most common endocrine disorders affecting million people in the world. The current prevalence of 5.5% and the expected rise to 8.2% by 2030 renders diabetes in Bangladesh a major public health problem. All forms of diabetes increase the risk of long-term complications like diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic foot ulcer, stroke, heart disease, cardiovascular disease, damage blood vessels. Hyperuricemia and high serum creatinine level are risk are risk for diabetic nephropathy.
Methodology: The aim of this study was to evaluate the uric acid and serum creatinine level among diabetic patients. Diabetic subjects were 100 and control subjects 50 were attending out-patient department during 15 May to 15 September 2022. Patients with known diabetic disease were excluded. Blood samples were analyzed for blood sugar (glucose), uric acid and creatinine on basis of reference laboratory standards in the institute.
Results: Out of 100 diabetic subjects and 50 control subjects, the mean of uric acid level in control group was found to be 5.30 mmol/L whereas in diabetics it was found to be 6.50 mmol/L. The mean creatinine levels in controls was found to be 0.88 mg/dL and in diabetics, it was found to be 2.02 mg/dL.
Conclusion: Uric acid and creatinine are useful, simple biomarkers and prognostic tests of renal failure in diabetic patients.
Keywords: DM, Uric acid, Serum Creatinine, Nephropathy
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