E ISSN: 2583-049X
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International Journal of Advanced Multidisciplinary Research and Studies

Volume 3, Issue 1, 2023

Transgenic Plants in Biopharmaceutical Production



Author(s): Neerja Masih

Abstract:

At present there has been a considerable increase in the application of plants biotechnology for production of variety of commercially valuable products for human health care use. Earlier the plants cell or their extract are used for the treatment of human disease and utilized to produced biopharmaceutical protein and peptides as they are simply transformed and provide a cheap source of protein. Many biotechnology companies are engaged in actively developing, field testing and patenting plants expression. So, plant-based production system can be used as an alternative of existing system it is advantageous to use but gained lower social acceptance. Several strategies are involved for yield. Biopharmaceutical also includes a recombinant vaccine, monoclonal antibodies, therapeutic and nutraceutical proteins. The two major challenges are low yield and non -mammalian glycosylation that oppose against full utilisation of plants as alternative Bioreactor to mammalian cell culture. In this review attempt has been made to focus on plants-based production system for recombinants protein production, strategies involved in plants transformation and its potential to produce biopharmaceutical.


Keywords: Biopharmaceutical Protein, Plant Based Vaccines, Antibodies, Nutraceutical

Pages: 374-381

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