E ISSN: 2583-049X
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International Journal of Advanced Multidisciplinary Research and Studies

Volume 3, Issue 3, 2023

Comparison of Biochemical Parameter of Rheumatoid Arthritis Patients and Healthy Individuals



Author(s): Dr. Sadia Hassan, Dr. Ferdous Towhid, Dr. Kartick Chanda Shaha, Dr. Nazma Akther, Dr. Md. Shafiqur Rahman

Abstract:

Objective: The aim of the present study was to compare the biochemical parameter of Rheumatoid arthritis patients and healthy individuals.

Methods: A cross sectional study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2016 to June 2017. According to selection criteria one hundred subjects were selected with the age ranging from 20-60 years and equally divided into two groups. Group-A fifty diagnosed case of rheumatoid arthritis patients attending in the OPD of Arthritis Care and Research Centre and SLE Clinic, Department of Medicine, Dhaka Medical College Hospital and Group-B fifty apparently healthy individuals. The study parameters were BMI, CRP, ESR, urinalysis and blood pressure. The results were compared statistically between two groups.

Results: BMI was significantly higher in Group A (28.5 ±4.8) than Group B (21.1 ± 3.7) but there were no significant difference of systolic blood pressure and diastolic blood pressure in-between two groups. Mean ± SD of ESR, CRP levels were significantly (<0.05) higher in Group A than Group B. Frequency of proteinuria and hematuria in Group A, 18% were urinary protein positive and 14% were hematuria positive

Conclusion: BMI is significantly higher in rheumatoid arthritis patients. ESR and CRP levels were significantly higher in rheumatoid arthritis patients. Proteinuria and hematuria is present in some rheumatoid arthritis patients, so renal function status should be checked regularly.


Keywords: Rheumatoid Arthritis, ESR, CRP

Pages: 39-41

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