Frequency of Deranged Lipid Profile in Patients of Acute Pancreatitis

Objectives: To determine the frequency of deranged lipid profile in patients of acute pancreatitis.

Study Design: Descriptive Cross-sectional study

Setting: Department of Surgery, Khyber Teaching Hospital, Peshawar.

Duration: From January 2023 to May 2023.

Methodology: After attaining approval from the Hospital ethical committee, 100 diagnosed Patients of acute pancreatitis of all ages irrespective of the gender were included in the study taking into account specifically the lipid profile, Glasgow score, age, gender, residence of the patient and educational status of the patients. The data was compiled on a proforma, and SPSS v23 was used to analyse it. The technique utilised was non-probability consecutive sampling. In this study, the categorical variables were described in terms of frequency and percentages; on the other hand, continuous variables were showed in mean and standard deviations.

Results:

55 (55%) of the 100 patients that were enrolled in this study were male, and 45% were female. The average age was 30.5 years +/- SD, ranging from 21 to 70 years. With regard to LDL levels, 48 patients had deranged LDL levels, 51 patients had deranged serum triglycerides levels and for HDL levels there was no significant derangement seen. The overall frequency of deranged lipid profile in patients with acute pancreatitis is 51.2%. Considering the Glasgow scoring which is used to determine the severity of acute pancreatitis, out of the total 100 patients about 20 presented with zero score, 45 presented with 1 score,30 with 2 score and only 8 patients presented with 3 Glasgow score.

Conclusion:

Taking the overall frequency of deranged lipid profile in patients with acute pancreatitis as 51.2%. We can safely conclude that hyperlipidemia is frequent in patients of acute pancreatitis and can be a considerable cause in many cases where other causes are ruled out.